Even in the general obscurity of the First Dynasty, the fourth successor of King Aha (excluding Merneith, though she may have been Queen Regnant, but this is still uncertain) left little trace of what was probably a fairly short reign. It may be that it marked a time of unrest, for the process of the Unification of the Two Lands on which Aha and his successors had set out, was not achieved without opposition from the diverse regions of the country. Anedjib seems, however, to have been particularly associated with Memphis (at least according to a somewhat later record), perhaps being the first king to reside in what was to become the most celebrated of Egypt's cities.

Anedjib was buried in a relatively modest tomb in Abydos, though it is notable for its wooden floor. He took over sixty of his retainers with him into the afterlife, however.