Ramose was the vizier who served the kings Amenhotep III and his son Amenhotep IV-Akhenaten and recorded various of his relations in his fine tomb at Thebes (TT 55). Amongst those whom he sought to have with him in the afterlife were his mother Ipuia and Maiy, the Overseer of the Royal Horses and his wife, Werel.

The reliefs and paintings from Ramose's tomb are probably the finest surviving from the Amarna period. They record much of the life at court and the rituals associated with the newly introduced worship of the Aten.