A contemporary of King Ramesses II when he was Crown Prince, Ameneminet was one of Ramesses' closest companions and served him in a variety of important posts when he succeeded to the kingship. He was the son of the influential High Priest of Amun, Wennufer, and his uncle was High Priest of Min and Isis at Koptos.

Ameneminet's official career began when he was appointed a Royal Charioteer and the king's Superintendent of Horse. He went on to become Royal Envoy to All Foreign Lands, a very high rank at the court; in this capacity he reported to the king directly on all issues affecting Egypt's relations with her neighbors, a department of state on which Ramesses placed great importance. Later still, he was Chief of Works and Commander of the Medjay Militia.