Aper-El was a high official in the service of King Amenhotep III; he was buried at Saqqara with his wife and his son, Huy, who was a general of chariotry.

He became vizier to the king and thus his highest ranking official. Despite this, little is known of him other than that he was a 'child of the kap', the royal academy in which young foreign princes and others of good birth were educated with the royal children. It has been suggested that Aper-El's name indicates an Asiatic, possibly Syrian, origin.